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Recruiting NCT05723081

Oklahoma Study of Native American Pain Risk III: Stress and Resilience

Trial Parameters

Condition Discrimination, Racial
Sponsor University of Oklahoma
Study Type OBSERVATIONAL
Phase N/A
Enrollment 220
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-02-03
Completion 2027-03-31

Brief Summary

The goal of this observational study is to learn about the relationship between environmental structural racism and discrimination and chronic pain risk in Native American adults. The main questions it aims to answer are: 1. How does environmental structural racism and discrimination affect chronic pain-promoting mechanisms in Native Americans? 2. What psychosocial factors buffer the negative effects of environmental structural racism and discrimination on chronic pain-promoting mechanisms?

Eligibility Criteria

Inclusion Criteria: * Self-identify as Native American/American Indian Exclusion Criteria: * \<18 years of age * Self-reported history of cardiovascular, neuroendocrine, musculoskeletal, or neurological disorders * Surrent chronic pain, defined as persistent, bothersome pain on more days than not for at least 3 months) * Self-reported current substance dependence * Sse of medication that could interfere with testing (e.g., recent use of analgesics, antidepressants, or anti-anxiety medications) * Inability to speak English * Current psychosis (assessed by Psychosis Screening Questionnaire) * Serious cognitive impairment (assessed by \<20 score on the Montreal Cognitive Assessment \[MoCA\]) * Possible peripheral neuropathy (assessed by nerve conduction study)

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