OCTA in Cardiovascular Disease and Healthy Controls
Trial Parameters
Brief Summary
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy individuals. The study will be conducted at the Clinical Research Centre (CRC), Department of Nephrology and Hypertension at the University of Erlangen-Nuremberg.
Eligibility Criteria
Inclusion Criteria for patients with cardiovascular disease: * cardiovascular disease defined as one or more of the following: arterial hypertension, type 2 diabetes mellitus, chronic kidney disease, heart failure Inclusion Criteria for healthy individuals: * BMI 18-29.9 kg/m2 * Non-smoker * Good general health, as determined by study personnel based on assessments of previous visits, including anamnesis, vital signs, physical examination and clinical laboratory parameters. Exclusion criteria for patients with cardiovascular disease: * Active ophthalmological (retinal) disease resulting in impaired visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema). Exclusion criteria for healthy individuals: * Active ophthalmological (retinal) disease with reduced visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema). * clinically relevant deviation in physical examination, vital signs, or laboratory parameters (based on the physician's clinical j