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healthy participants
Total Trials
12
Recruiting Now
12
Trial Phases
Phase 1
Clinical trials often recruit healthy volunteers for Phase 1 pharmacokinetic and safety studies, vaccine immunogenicity assessments, and normal physiological reference studies. These trials are essential for establishing safe dose ranges and understanding how drugs behave in the absence of disease before testing in patient populations.
Healthy volunteer studies include first-in-human drug trials, vaccine efficacy (flu, RSV, COVID-19, malaria), microbiome intervention studies, exercise physiology research, and device safety assessments. Compensation is often provided; eligibility typically requires no significant medical history and a negative drug screen.
Healthy volunteer trials require participants to be in good general health with no significant medications. Many exclude smokers, pregnant individuals, and those with recent prior trial participation.
Frequently Asked Questions — healthy participants Clinical Trials
How many clinical trials are currently recruiting for healthy participants?
ClinicalMetric currently tracks 12 actively recruiting clinical trials for healthy participants, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for healthy participants?
healthy participants research spans Phase 1 (5 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a healthy participants clinical trial?
Eligibility criteria for healthy participants trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1 5
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT05942066
Recruiting
Enrollment
200 pts
Location
Italy
Sponsor
Tethis S.p.A.
NCT07232121 Phase 1
Recruiting
Enrollment
48 pts
Location
Australia
Sponsor
Dragonfly Therapeutics
NCT07412353 Phase 1
Recruiting
Enrollment
74 pts
Location
China
Sponsor
CSPC ZhongQi Pharmaceutical Te...
NCT07209202
Recruiting
Enrollment
40 pts
Location
United States
Sponsor
Touro University, California
NCT07267845
Recruiting
Enrollment
80 pts
Location
Ireland
Sponsor
Nanjing Nutrabuilding Bio-tech...
NCT07411248
Recruiting
Enrollment
30 pts
Location
Turkey (Türkiye)
Sponsor
Biruni University
NCT07419698 Phase 1
Recruiting
Enrollment
44 pts
Location
China
Sponsor
Shanghai JMT-Bio Inc.
NCT07237087
Recruiting
Enrollment
40 pts
Location
Switzerland
Sponsor
University of Zurich
NCT06961747 Phase 1
Recruiting
Enrollment
15 pts
Location
United States
Sponsor
UCB Biopharma SRL
NCT07469085 Phase 1
Recruiting
Enrollment
60 pts
Location
China
Sponsor
Shanghai Synvida Biotechnology...
NCT05346094
Recruiting
Enrollment
938 pts
Location
China
Sponsor
Chinese Academy of Medical Sci...
NCT07436260
Recruiting
Enrollment
150 pts
Location
Poland
Sponsor
Dawid Madej
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology