← Back to Clinical Trials
Recruiting Phase 3 NCT05992883

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis

Trial Parameters

Condition Thumb Osteoarthritis
Sponsor Mayo Clinic
Study Type INTERVENTIONAL
Phase Phase 3
Enrollment 240
Sex ALL
Min Age 40 Years
Max Age N/A
Start Date 2023-07-28
Completion 2026-12-31
Interventions
KetorolacTriamcinolone

Brief Summary

The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis. One injection is ketorolac (an NSAID) and the other is triamcinolone (a corticosteroid).

Eligibility Criteria

Inclusion Criteria: * Adults \>40 years of age * Pain at the thumb base brought on by direct pressure (grind test) and with movement * Pain resistant to previous conservative management (including over the counter medications (ibuprofen/acetaminophen), icing, splinting/braces, or topical analgesics) * Radiological observation indicative of arthritis based on the Eaton-Littler classification system (stages 1 through 4) * Patient understands the protocol and signed the informed consent * Patient is covered by health insurance Exclusion Criteria: * • Known allergy to either of the treatment products * Patient's analgesic treatment regimen or other modalities of managing symptoms/pain associated with their hand pathology was modified within four weeks before trial inclusion * Symptomatic Scaphoid-trapezial arthritis present * Localized or systemic infection * Previous thumb surgery on study thumb * Previous thumb injury on study thumb * Patient with inflammatory arthritis (e.g., rheumatoid

Related Trials