NCT06874309 Non-invasive Brain Stimulation to Prepare the Patient for Bariatric Surgery (REBAS)
| NCT ID | NCT06874309 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Masaryk University |
| Condition | Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 65 participants |
| Start Date | 2024-05-01 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 65 participants in total. It began in 2024-05-01 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Obesity is a chronic metabolic condition characterized by excessive accumulation of body fat, which triggers physiological mechanisms that increase the risk of a wide range of health problems. The most effective treatment for severe obesity is metabolic-bariatric surgery, which can lead to a 15-20% weight reduction, significantly lowering the risks of illness and death. However, the success of this surgery can be threatened by poor eating habits after the procedure. The main goal of this study is to enhance the long-term effectiveness of bariatric surgery by combining it with non-invasive brain stimulation (tDCS) targeting inhibitory centers before the operation. Additionally, the investigators aim to comprehensively monitor patients before and after surgery, focusing on investigating changes in brain function associated with the achieved weight loss.
Eligibility Criteria
Inclusion Criteria: * Subjects with severe or morbid obesity (determined by BMI \> 35 or 40 kg/m2, respectively) eligible for BS treatment in compliance with the current guidelines * Subjects who meet reduced control over eating behavior (disinhibition) criteria in the Eating Habits Questionnaire Exclusion Criteria: * Subjects unable to provide informed consent and those unable to understand and cooperate with study-related procedures (based on the physician's discretion) * Subjects with a personal history of ischemic heart disease, myocardial infarction, stroke, heart failure, and atrial fibrillation * Subjects who have already undergone BS treatment in the past * Pregnant subjects or subjects that plan on becoming pregnant during the study. * Subjects deemed unsuitable for the study based on expert evaluation (e.g., by a physician or neuropsychologist) will be excluded. * Subjects with dreadlocks (problematic for the EEG)
Contact & Investigator
Irena Rektorová, Prof.
PRINCIPAL INVESTIGATOR
Cetral European Institute of Technology
Frequently Asked Questions
Who can join the NCT06874309 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06874309 currently recruiting?
Yes, NCT06874309 is actively recruiting participants. Contact the research team at petra.zemankova@mail.muni.cz for enrollment information.
Where is the NCT06874309 trial being conducted?
This trial is being conducted at Brno, Czechia, Brno, Czechia.
Who is sponsoring the NCT06874309 clinical trial?
NCT06874309 is sponsored by Masaryk University. The principal investigator is Irena Rektorová, Prof. at Cetral European Institute of Technology. The trial plans to enroll 65 participants.
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