NCT07525505 Nigella Sativa Oil for Eczematous Otitis Externa
| NCT ID | NCT07525505 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bezmialem Vakif University |
| Condition | Eczema/Atopic Dermatitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 85 participants |
| Start Date | 2026-01-12 |
| Primary Completion | 2026-06 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 85 participants in total. It began in 2026-01-12 with a primary completion date of 2026-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Eczematous otitis externa is a common inflammatory condition of the external auditory canal characterized by itching, discomfort, discharge, and pain. Topical corticosteroids are widely used for treatment; however, alternative therapies with fewer side effects are of increasing interest. This study aims to compare the efficacy of Nigella sativa (black seed) oil and mometasone furoate ear drops in the treatment of eczematous otitis externa. Nigella sativa is a natural product with known anti-inflammatory and antimicrobial properties. In this randomized, controlled clinical trial, adult patients with eczematous otitis externa will be assigned to receive either Nigella sativa oil or mometasone furoate ear drops for 10 days. Clinical symptoms and inflammatory findings will be evaluated at baseline and after treatment. The objective of this study is to determine whether Nigella sativa oil is an effective and safe alternative to topical corticosteroid therapy.
Eligibility Criteria
Inclusion Criteria: * Adult patients aged 18 years and older * Clinical diagnosis of eczematous otitis externa confirmed by otoscopic examination * Presence of at least one symptom related to the affected ear (itching, discomfort, otorrhea, or pain) * Willingness to participate and ability to provide written informed consent Exclusion Criteria: * Known hypersensitivity or allergic reaction to Nigella sativa oil or mometasone furoate * Use of topical or systemic corticosteroids or other ear medications within a defined period prior to enrollment * Presence of acute otitis externa of infectious origin requiring antibiotic treatment * History of ear surgery or structural abnormalities of the external auditory canal * Severe systemic disease or condition that may interfere with study participation * Pregnant or breastfeeding women
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07525505 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Eczema/Atopic Dermatitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07525505 currently recruiting?
Yes, NCT07525505 is actively recruiting participants. Contact the research team at nzndegirmenci@hotmail.com for enrollment information.
Where is the NCT07525505 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07525505 clinical trial?
NCT07525505 is sponsored by Bezmialem Vakif University. The trial plans to enroll 85 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.