NCT05277519 Neuroplasticity After Proprioceptive Rehabiliation
| NCT ID | NCT05277519 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Institut National de la Santé Et de la Recherche Médicale, France |
| Condition | Stroke |
| Study Type | OBSERVATIONAL |
| Enrollment | 56 participants |
| Start Date | 2022-06-16 |
| Primary Completion | 2026-06-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 56 participants in total. It began in 2022-06-16 with a primary completion date of 2026-06-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the neuroplastic changes during and after instrumented proprioceptive rehabilitation relying on sequences of muscle vibration in subacute stroke stages.
Eligibility Criteria
Inclusion Criteria: * hemiparesis at least transient in lower limb following an acquired brain injury (stroke or traumatic brain injury) * French spoken * Affiliated to a French social insurance * No previous traumatic, vascular or neurodegenerative injuries * Having presented during the acute phase or presenting a motor deficit of one of the lower limbs * Presenting an absence of autonomy of walking at the entrance of the rehabilitation department * In the sub-acute phase, i.e. from 15 days to 6 months after the accident * Presenting moderate cognitive disorders allowing them to understand instructions and give their consent Exclusion Criteria: * strong cognitive disorders * maintenance of justice, tutelage, legal guardianship * Pregnancy and breastfeeding * Outpatients who do not have weekly follow-up in the rehabilitation department
Contact & Investigator
Eleonore Bayen, MD, PhD
PRINCIPAL INVESTIGATOR
Sorbonne University - AP-HP (Pitié-Salpêtrière Hospital)
Frequently Asked Questions
Who can join the NCT05277519 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05277519 currently recruiting?
Yes, NCT05277519 is actively recruiting participants. Contact the research team at veronique.marchand-pauvert@inserm.fr for enrollment information.
Where is the NCT05277519 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT05277519 clinical trial?
NCT05277519 is sponsored by Institut National de la Santé Et de la Recherche Médicale, France. The principal investigator is Eleonore Bayen, MD, PhD at Sorbonne University - AP-HP (Pitié-Salpêtrière Hospital). The trial plans to enroll 56 participants.
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