NCT05492188 Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI
| NCT ID | NCT05492188 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of South Carolina |
| Condition | Spinal Cord Injuries |
| Study Type | INTERVENTIONAL |
| Enrollment | 15 participants |
| Start Date | 2023-03-27 |
| Primary Completion | 2027-01-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 15 participants in total. It began in 2023-03-27 with a primary completion date of 2027-01-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure. The study involves approximately 50 visits with a total study duration of about 6.5 months (3 months for baseline and training phases followed by 1 month and 3 month follow-up visits).
Eligibility Criteria
Inclusion Criteria: 1. neurologically stable (\>1 year post SCI) 2. medical clearance to participate 3. ability to stand with or without an assistive device for at least 3 minutes at a time 4. expectation that current medication will be maintained without change for at least 3 months (stable use of anti-spasticity medication is accepted) 5. For participants with neuropathic pain, the area of neuropathic pain must include lower leg. Exclusion Criteria: 1. motoneuron injury 2. known cardiac condition 3. medically unstable condition (incl. pregnancy) 4. cognitive impairment 5. uncontrolled peripheral neuropathy 6. frequent use of electrical spinal stimulation (either transcutaneous or epidural) for pain treatment 7. daily use of electrical stimulation to the leg 8. complete lack of cutaneous sensation around foot.
Contact & Investigator
Aiko Thompson, PhD
PRINCIPAL INVESTIGATOR
Medical University of South Carolina
Frequently Asked Questions
Who can join the NCT05492188 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Spinal Cord Injuries. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05492188 currently recruiting?
Yes, NCT05492188 is actively recruiting participants. Contact the research team at stecb@musc.edu for enrollment information.
Where is the NCT05492188 trial being conducted?
This trial is being conducted at Charleston, United States.
Who is sponsoring the NCT05492188 clinical trial?
NCT05492188 is sponsored by Medical University of South Carolina. The principal investigator is Aiko Thompson, PhD at Medical University of South Carolina. The trial plans to enroll 15 participants.