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neuropathic pain

Total Trials
11
Recruiting Now
11
Trial Phases
Phase 1, Phase 2

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — neuropathic pain Clinical Trials

How many clinical trials are currently recruiting for neuropathic pain?
ClinicalMetric currently tracks 11 actively recruiting clinical trials for neuropathic pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 11. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for neuropathic pain?
neuropathic pain research spans Phase 1 (1 trial), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a neuropathic pain clinical trial?
Eligibility criteria for neuropathic pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
2
Top Sponsors
Saglik Bilimleri Universitesi 1 trial
Izmir City Hospital 1 trial
Afyonkarahisar Health Sciences University 1 trial
Alcamena Stem Cell Therapeutics 1 trial
Karel Hanssens 1 trial

Recruiting Clinical Trials

NCT07420192
Recruiting
Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees
Enrollment
20 pts
Location
Turkey (Türkiye)
Sponsor
Saglik Bilimleri Universitesi
View Trial →
NCT07057128
Recruiting
Neuropathic Characteristics of Subacromial Pain Syndrome
Enrollment
82 pts
Location
Turkey (Türkiye)
Sponsor
Izmir City Hospital
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NCT06750692
Recruiting
Comparison of the Effects of Mirror Therapy,rTMS and Robotic-assisted Hand Therapy in Stroke Patients
Enrollment
120 pts
Location
Turkey (Türkiye)
Sponsor
Afyonkarahisar Health Sciences...
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NCT07363395 Phase 1
Recruiting
Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults
Enrollment
72 pts
Location
United States
Sponsor
Alcamena Stem Cell Therapeutic...
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NCT06775535
Recruiting
Neuronal Activation Accuracy in Closed-loop Spinal Cord Stimulation
Enrollment
12 pts
Location
Belgium
Sponsor
Karel Hanssens
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NCT06216717
Recruiting
Study of the Location of Motor Cortical Stimulation Electrodes in Chronic Neuropathic Refractory Patients
Enrollment
100 pts
Location
France
Sponsor
Centre Hospitalier Universitai...
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NCT05351801 Phase 2
Recruiting
Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain
Enrollment
320 pts
Location
United States
Sponsor
VA Office of Research and Deve...
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NCT07304401
Recruiting
Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy
Enrollment
20 pts
Location
Netherlands
Sponsor
Rijnstate Hospital
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NCT06869928
Recruiting
Implementation of the Pain and Irritability of Unknown Origin (PIUO) Pathway in Community Pediatric Practices
Enrollment
20 pts
Location
Canada
Sponsor
University of British Columbia
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NCT06915662 Phase 2
Recruiting
Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap
Enrollment
20 pts
Location
United States
Sponsor
Massachusetts General Hospital
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NCT06798181
Recruiting
Neuropathic Pain and Type II Diabetic Patients
Enrollment
128 pts
Location
Turkey (Türkiye)
Sponsor
Bilecik Seyh Edebali Universit...
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Related Conditions

quality of life (2) symptomatic neuroma (1) phantom limb pain after amputation (1) residual limb pain (1) lower extremity amputations (1) central sensitization (1) subacromial pain syndrome (1) stroke (1) upper extremity dysfunction (1) neurologic disorder (1) chronic pain (1) persistent spinal pain syndrome type 2 (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology