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Recruiting NCT07702539

NCT07702539 NASA Exercise Prebreathe Study

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Clinical Trial Summary
NCT ID NCT07702539
Status Recruiting
Phase —
Sponsor Duke University
Condition Decompression Sickness
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2026-08-13
Primary Completion 2027-02-27

Eligibility & Interventions

Sex All sexes
Min Age 30 Years
Max Age 60 Years
Study Type INTERVENTIONAL
Interventions
Oxygen Prebreathe and Hypobaric Exposure

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 30 participants in total. It began in 2026-08-13 with a primary completion date of 2027-02-27.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study evaluates oxygen prebreathe protocols and exercise conditions to reduce risk of decompression sickness during simulated extravehicular activity. Healthy adult volunteers will undergo oxygen prebreathe followed by hypobaric chamber exposure with monitoring for symptoms and ultrasound detection of bubbles.

Eligibility Criteria

Inclusion Criteria: * Non-smoking volunteers aged 30-60 years * Able to meet VO2 peak requirements (\>35 ml/kg/min males, \>30 ml/kg/min females) Exclusion Criteria: * Pregnancy * Lung disease, heart disease, hypertension, or diabetes * Musculoskeletal pain conditions * Requirement for regular medications such as analgesics

Contact & Investigator

Principal Investigator

Richard Moon

PRINCIPAL INVESTIGATOR

Duke University

Frequently Asked Questions

Who can join the NCT07702539 clinical trial?

This trial is open to participants of all sexes, aged 30 Years or older, up to 60 Years, studying Decompression Sickness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07702539 currently recruiting?

Yes, NCT07702539 is actively recruiting participants. Visit ClinicalTrials.gov or contact Duke University to inquire about joining.

Where is the NCT07702539 trial being conducted?

This trial is being conducted at Durham, United States.

Who is sponsoring the NCT07702539 clinical trial?

NCT07702539 is sponsored by Duke University. The principal investigator is Richard Moon at Duke University. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology