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Duke University

Total Trials
37
Recruiting
37
Phases
Phase 4, Phase 1, Phase 2, Phase 1

Duke University is a clinical research sponsor with 37 registered studies on ClinicalTrials.gov, of which 37 are actively recruiting participants. Research covers conditions including Retinal Disease, Glaucoma, Optic Nerve Diseases, Autoimmune Diseases.

The trial portfolio spans Phase 4, Phase 1, Phase 2, Phase 1 studies, reflecting a pipeline that may include early-stage safety evaluations, mid-stage efficacy assessments, and large-scale confirmatory trials. All studies listed here are sourced directly from ClinicalTrials.gov and updated daily.

Frequently Asked Questions — Duke University

How many clinical trials has Duke University sponsored?
ClinicalMetric currently tracks 37 clinical trials sponsored by Duke University, of which 37 are actively recruiting participants. These trials cover conditions including Retinal Disease, Glaucoma, Optic Nerve Diseases. Trial counts are updated daily from ClinicalTrials.gov and reflect currently registered studies.
What therapeutic areas does Duke University research focus on?
Duke University clinical trials span Retinal Disease, Glaucoma, Optic Nerve Diseases, Autoimmune Diseases, Pregnancy Related, and additional conditions. The research pipeline includes Phase 4, Phase 1, Phase 2, Phase 1 trials, reflecting work from early-stage safety evaluation through large-scale efficacy studies.
How do I participate in a Duke University clinical trial?
To participate in a Duke University trial, review the active studies listed on this page, check each trial's specific eligibility criteria on ClinicalTrials.gov, and contact the trial site directly—not the sponsor's headquarters. Trial sites are academic medical centers, hospitals, or specialized research clinics. Your physician can facilitate a referral. ClinicalMetric lists all Duke University trials with current recruitment status updated daily.

Clinical Trials by Duke University

NCT06139523
Recruiting

Optimize Pediatric OCT Imaging

Retinal Disease
NCT03276923
Recruiting

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

Autoimmune Diseases
NCT06983678
Recruiting

Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

Tobacco Use
NCT07215507
Recruiting

Timing of Physician Rounds for Antepartum Patients

Physician Rounds
NCT06141993
Recruiting

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

Prostate Cancer
NCT05929898
Recruiting

MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants

Motivation
NCT04140344
Recruiting

The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions

Lumbar Spine Degeneration
NCT07348614 Phase 4
Recruiting

Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia

Knee Stiffness After Total Knee Arthroplasty
NCT07158814 Phase 4
Recruiting

Safety of RSV Preventive Monoclonal Antibody

Fever
NCT07278804
Recruiting

Development of a Pain Control Options Menu for IUD Insertion

IUD Insertion Pain
NCT03310905
Recruiting

Abdominal Wall Transplant

Transplant;Failure,Kidney
NCT06765642
Recruiting

The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.

Stroke
NCT04933435
Recruiting

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

Liver Cancer
NCT07101640 Phase 1, Phase 2
Recruiting

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia (BPD)
NCT06627764
Recruiting

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

Substance Abuse
NCT05309655
Recruiting

Cardiac Outcomes With Near-Complete Estrogen Deprivation

Breast Cancer
NCT06854718
Recruiting

Pain With Dementia

Pain
NCT05092126
Recruiting

Development & Validation of Preoperative Objective Physiological Evaluation

Cardiorespiratory Fitness
NCT06126744 Phase 1
Recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252

Recurrent High Grade Glioma
NCT06625684
Recruiting

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

Glioblastoma
NCT07471685
Recruiting

Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors

Cancer Survivorship
NCT01745237
Recruiting

Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis

Sarcoidosis
NCT07089901 Phase 4
Recruiting

Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and the Environment

Smoking
NCT00345930
Recruiting

DILIN - Prospective Study

Liver Diseases
NCT05905419
Recruiting

Neuroimaging of Opioid Phase (OPAL)

Chronic Pain
NCT06986304
Recruiting

Characterizing the Microvascular Environment of Bladder Cancer With Super-Resolution Ultrasound Localization Microscopy

Bladder Cancer
NCT05760898
Recruiting

Improving Hypertension Control in Rheumatoid Arthritis

Hypertension
NCT05480644
Recruiting

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

Brain Tumor, Primary
NCT05129345
Recruiting

Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US

Hypertension
NCT06545643
Recruiting

Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs

Epilepsy Intractable
NCT04639336
Recruiting

Cognitive and Neurological Pathologies in Pompe Disease

Pompe Disease
NCT05262907
Recruiting

Ventripoint Single Ventricle Study

Congenital Heart Disease
NCT03754725 Phase 1, Phase 2
Recruiting

Ferritin and Iron Burden in SAH sIRB

SAH
NCT07159269
Recruiting

Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

Cardiovascular Disease Acute
NCT06087029
Recruiting

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

Type B Aortic Dissection
NCT07234201
Recruiting

Virtual Reality Use for ICU Mobility

Intensive Care Unit ICU
NCT04107181
Recruiting

Pilot Study for Speculum Free Cervical Cancer Screening

Cervical Cancer
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology