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Recruiting NCT06671886

NCT06671886 NAFLD Clinical Care Pathway

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Clinical Trial Summary
NCT ID NCT06671886
Status Recruiting
Phase
Sponsor VA Office of Research and Development
Condition NAFLD
Study Type INTERVENTIONAL
Enrollment 32 participants
Start Date 2024-02-02
Primary Completion 2028-01-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
All Conditions
Interventions
E-trigger

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 32 participants in total. It began in 2024-02-02 with a primary completion date of 2028-01-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Non-alcoholic fatty liver disease (NAFLD) is a new condition that has become the most common chronic liver disease in the world and a main cause of liver cirrhosis, liver failure and liver cancer. Obesity and diabetes, conditions that are very common among Veterans are the main risk factors for NAFLD. Therefore, the burden of NAFLD and its complications among Veterans is substantial. However, most VA patients with NAFLD are undiagnosed and untreated, and their care is not consistent with practice guidelines. The NAFLD Clinical Care Pathway (NCCP) intervention seeks to close this major gap in the care of Veterans by automatically identifying patients at risk of NAFLD, calculating their risk scores of having severe NAFLD, and educating the primary care providers on the diagnosis and treatment of NAFLD. This clinical trial will test the benefit of this NCCP intervention against usual care in increasing the rates of NAFLD diagnosis as well as referral to and enrollment in appropriate treatment. The study will also identify barriers and promotors of future NCCP implementation.

Eligibility Criteria

Inclusion Criteria: Patient Aligned Care Teams (PACT) at the Michael E. DeBakey VA Medical Center Exclusion Criteria: * The investigators will exclude PACTs with unstable leadership (i.e., pending departure, vacancy) at time of randomization. * PACTs participating in the focus groups in Aim 1 will be excluded in Aim 2 to avoid cross contamination. * PACTs meeting the following criteria will be excluded from randomization in Aim 2: * PACTs who do not treat NAFLD, * PACTs not located at the main hospital, * PACTs with less than 100 visits within 3 months.

Contact & Investigator

Central Contact

Hashem B El-Serag, MD MPH

✉ Hashem.El-Serag@va.gov

📞 (713) 794-8640

Principal Investigator

Hashem B. El-Serag, MD MPH

PRINCIPAL INVESTIGATOR

Michael E. DeBakey VA Medical Center, Houston, TX

Frequently Asked Questions

Who can join the NCT06671886 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying NAFLD. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06671886 currently recruiting?

Yes, NCT06671886 is actively recruiting participants. Contact the research team at Hashem.El-Serag@va.gov for enrollment information.

Where is the NCT06671886 trial being conducted?

This trial is being conducted at Houston, United States.

Who is sponsoring the NCT06671886 clinical trial?

NCT06671886 is sponsored by VA Office of Research and Development. The principal investigator is Hashem B. El-Serag, MD MPH at Michael E. DeBakey VA Medical Center, Houston, TX. The trial plans to enroll 32 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology