Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
Trial Parameters
Brief Summary
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are: * to evaluate the residual neuroplastic processes in DOC state related to music exposure * to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation * to evaluate the impact of this intervention on caregiver's burden and psychological distress. Participants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.
Eligibility Criteria
Inclusion Criteria: * Age \> 18 years * Post-stroke aphasia * Post-stroke neglect * Patients with disorders of consciusness (DOC) Exclusion Criteria: * No auditory injury * no hystory of neurological disease * No hystory of psychiatric disease * Previous stroke * use of alcohol and drugs * premorbid dementia