NCT06770062 Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study
| NCT ID | NCT06770062 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | Left Ventricular Systolic Dysfunction |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-01-20 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2025-01-20 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research is to determine the feasibility of a larger, future study proposing a multimodal approach using cardiac CT and MRI to assess the risk of developing left ventricular (LV) systolic dysfunction in patients with mitral regurgitation (MR).
Eligibility Criteria
Inclusion Criteria: * Age \>= 18 * Male or Female * A diagnosis of severe chronic primary mitral regurgitation * Undergoing isolated robotic mitral annuloplasty at Mayo Clinic Rochester * Patients must have the ability to consent or have an appropriate representative available to do so. Exclusion Criteria: * Prior valve intervention, * Concomitant valve surgery at the time of mitral annuloplasty (e.g. tricuspid annuloplasty, aortic valve replacement). * Concomitant \>= moderate regurgitation or stenosis in any other valve by preoperative echocardiography * History of prior myocardial infarction * History of cardiomyopathy unrelated to mitral regurgitation (e.g. dilated, hypertrophic, infiltrative) * Pregnancy. Women of childbearing potential will be verbally screened by clinical staff during as part of routine pre-MRI evaluation. If a subject is unsure whether they could be pregnant, a negative pregnancy test will be performed prior to scanning. * Implantable devices that would be a contraindication to MRI * Severe allergy to gadolinium MRI contrast
Contact & Investigator
Arman Arghami, MD, MPH
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT06770062 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Left Ventricular Systolic Dysfunction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06770062 currently recruiting?
Yes, NCT06770062 is actively recruiting participants. Contact the research team at cvsurgresearch@mayo.edu for enrollment information.
Where is the NCT06770062 trial being conducted?
This trial is being conducted at Rochester, United States.
Who is sponsoring the NCT06770062 clinical trial?
NCT06770062 is sponsored by Mayo Clinic. The principal investigator is Arman Arghami, MD, MPH at Mayo Clinic. The trial plans to enroll 30 participants.