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RecruitingNCT04461301

Multimodal Prehabilitation for Surgery in the Elderly: a Randomised, Prospective, Multicenter, Multidisciplinary Trial

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Trial Parameters

ConditionFrail Elderly Syndrome
SponsorInsel Gruppe AG, University Hospital Bern
Study TypeINTERVENTIONAL
PhaseN/A
Enrollment466
SexALL
Min Age65 Years
Max AgeN/A
Start Date2022-02-01
Completion2026-07-30
Interventions
Multimodal Prehabilitation

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Brief Summary

This multicentric, randomised controlled trial is to the investigators knowledge the first implementation of a multimodal, multidisciplinary prehabilitation approach using knowledge from different specialties to lower complications and to increase cost effectiveness after major surgery in elderly, frail patients.

Eligibility Criteria

Inclusion Criteria: * Written informed consent * comorbid (≥ASA 3) * pre-existing fitness deficit: AT\<11ml/kg/min respectively VO2peak\<14ml/kg/min if AT unavailable or VE/VCO2 slope \> 33 * scheduled for major urologic, thoracic, visceral, orthopaedic or cardiovascular surgery * screening at least 2 weeks prior to surgery Exclusion Criteria: * Paralysis or patients with mobility problems (who are unable to exercise), * Premorbid conditions or orthopaedic impairments that contraindicate exercise, * Cognitive disabilities, * Chronic renal failure (need for dialysis) * Emergency procedures.

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