NCT04436991 Antibiotic Dosing in Geriatric Patients At the Emergency Department
| NCT ID | NCT04436991 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Ghent |
| Condition | Elderly Infection |
| Study Type | OBSERVATIONAL |
| Enrollment | 180 participants |
| Start Date | 2018-01-03 |
| Primary Completion | 2021-09-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 180 participants in total. It began in 2018-01-03 with a primary completion date of 2021-09-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In this pilot study, we will investigate whether - with the current dosing regimens, used in the Ghent University Hospital - pharmacodynamic targets regarding beta-lactam antibiotics (more specific Amoxicilline-Clavulanate, Piperacillin-Tazobactam and Temocillin) are attained in frail patients admitted to the geriatric department.
Eligibility Criteria
Inclusion Criteria: * Patients presenting at the emergency department and later on admitted to the geriatric department * Patient age 75 years or older * Patients with geriatric profile according to KATZ scale, G8 screening test or CIRS score. * Patient receiving antibiotic treatment (amoxicillin-clavulanate, piperacillin-tazobactam) * Intravenous access available for blood sampling. For measurement of the peak concentration an intravenous access other than the drug infusion line is required. Exclusion Criteria: * Admission to other units than the geriatric department incl. the ICU. * Absence of informed consent * Known hypersensitivity to beta-lactam antibiotics * Patients who received oral amoxicillin-clavulanate prior to admission will not be included in the iv. amoxicillin-clavulanate group.
Contact & Investigator
Tania Desmet, Dr.
PRINCIPAL INVESTIGATOR
University Hospital, Ghent
Frequently Asked Questions
Who can join the NCT04436991 clinical trial?
This trial is open to participants of all sexes, aged 75 Years or older, studying Elderly Infection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04436991 currently recruiting?
Yes, NCT04436991 is actively recruiting participants. Contact the research team at peter.depaepe@uzgent.be for enrollment information.
Where is the NCT04436991 trial being conducted?
This trial is being conducted at Ghent, Belgium.
Who is sponsoring the NCT04436991 clinical trial?
NCT04436991 is sponsored by University Hospital, Ghent. The principal investigator is Tania Desmet, Dr. at University Hospital, Ghent. The trial plans to enroll 180 participants.