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Recruiting NCT06453980

NCT06453980 Multimodal Investigation of Neural Plasticity

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Clinical Trial Summary
NCT ID NCT06453980
Status Recruiting
Phase
Sponsor University of Michigan
Condition Mild Cognitive Impairment
Study Type INTERVENTIONAL
Enrollment 80 participants
Start Date 2024-05-13
Primary Completion 2026-04-30

Eligibility & Interventions

Sex All sexes
Min Age 60 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
sham tDCSactive tDCS

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 80 participants in total. It began in 2024-05-13 with a primary completion date of 2026-04-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognitive impairment (MCI).

Eligibility Criteria

Inclusion Criteria: * Normal cognition for HC and diagnosis of Mild Cognitive Impairment (MCI) for MCI participants * Right-handedness * Magnetic resonance compatible, criteria that also apply for high definition transcranial direct current stimulation (HD-tDCS; e.g., absence of metallic or electronic implants in the upper body or head) Exclusion Criteria: * History of other contributing neurological or medical conditions known to affect cognitive functioning * Significant mental illness * Sensory impairments that limit ability to participate * History of alcohol or drug abuse/dependence

Contact & Investigator

Central Contact

Harini Babu, MSc

✉ hariniba@umich.edu

📞 734-647-3704

Principal Investigator

Alexandru Iordan, PhD

PRINCIPAL INVESTIGATOR

University of Michigan

Frequently Asked Questions

Who can join the NCT06453980 clinical trial?

This trial is open to participants of all sexes, aged 60 Years or older, studying Mild Cognitive Impairment. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06453980 currently recruiting?

Yes, NCT06453980 is actively recruiting participants. Contact the research team at hariniba@umich.edu for enrollment information.

Where is the NCT06453980 trial being conducted?

This trial is being conducted at Ann Arbor, United States.

Who is sponsoring the NCT06453980 clinical trial?

NCT06453980 is sponsored by University of Michigan. The principal investigator is Alexandru Iordan, PhD at University of Michigan. The trial plans to enroll 80 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology