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Recruiting NCT06453980

Multimodal Investigation of Neural Plasticity

Trial Parameters

Condition Mild Cognitive Impairment
Sponsor University of Michigan
Study Type INTERVENTIONAL
Phase N/A
Enrollment 80
Sex ALL
Min Age 60 Years
Max Age N/A
Start Date 2024-05-13
Completion 2026-04-30
Interventions
sham tDCSactive tDCS

Brief Summary

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognitive impairment (MCI).

Eligibility Criteria

Inclusion Criteria: * Normal cognition for HC and diagnosis of Mild Cognitive Impairment (MCI) for MCI participants * Right-handedness * Magnetic resonance compatible, criteria that also apply for high definition transcranial direct current stimulation (HD-tDCS; e.g., absence of metallic or electronic implants in the upper body or head) Exclusion Criteria: * History of other contributing neurological or medical conditions known to affect cognitive functioning * Significant mental illness * Sensory impairments that limit ability to participate * History of alcohol or drug abuse/dependence

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