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Recruiting NCT06448403

Multimodal Assesment of Alzheimer Patients

Trial Parameters

Condition Mild Cognitive Impairment
Sponsor Norwegian University of Science and Technology
Study Type OBSERVATIONAL
Phase N/A
Enrollment 60
Sex ALL
Min Age 65 Years
Max Age N/A
Start Date 2024-07-01
Completion 2030-12-29
Interventions
MRI Scanning64-channel EEGPolysomnography

Brief Summary

The goal of this study is to learn more about the changes in the brains of patients with cognitive impairment (MCI) and Alzheimer's Disease (AD). The main questions the study aims to answer are: 1. What findings can be used to earlier detect patients that will develop Alzheimers? 2. Which differences are seen between healthy and cognitively impaired patients? 3. Which differences are seen between patients with Alzheimers disease? Participants will undergo: * Cognitive tests * Magnetic resonance imaging (MRI) * Electroencephalography (EEG) * Blood sample collection * Fecal sample collection * A randomized group will undergo polysomnography analysis.

Eligibility Criteria

Inclusion Criteria: * MCI and AD according to relevant ICD-criterias. * Control cohort is age and gender matched with other cohorts. Exclusion Criteria: * Uneligibility for any of the planned neuroimagery devices (MRI, EEG) * AD diagnosis before the age of 65 (Early-onset AD). * Brain tumor * Traumtic head injury * Earlier neurosurgery * Other neyrodegenerative diseases (i.e Parkinson and ALS) * Diseases related to inflammation and auto-immunity (i.e MS)

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