| NCT ID | NCT06843980 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Moximed |
| Condition | Osteoarthritis, Knee |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-02-13 |
| Primary Completion | 2026-04-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2025-02-13 with a primary completion date of 2026-04-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment. This is the first randomized head-to-head study comparing outcomes from subjects treated with the MISHA Knee System.
Eligibility Criteria
Key Inclusion Criteria: 1. Activity exacerbated knee pain isolated to the medial compartment and not global in nature 2. WOMAC pain ≥ 40 3. Failed to find relief in non-surgical treatment modalities Key Exclusion Criteria: 1. Large medial osteophyte(s) or considerable extruded meniscus that may interfere with the placement or function of the device 2. Poor bone quality (e.g., bony erosion, osteopenia, osteoporosis) 3. Ligamentous instability 4. Active or recent knee infection 5. Inflammatory joint disease, including sequelae of viral infections 6. Suspected or documented allergy or hypersensitivity to cobalt, chromium, nickel or other metals 7. History of keloid, hypertrophic or contracture scaring 8. Propensity for restrictive scar formation or adhesions with prior procedures
Contact & Investigator
Rose S Weinstein
STUDY DIRECTOR
Moximed
Frequently Asked Questions
Who can join the NCT06843980 clinical trial?
This trial is open to participants of all sexes, studying Osteoarthritis, Knee. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06843980 currently recruiting?
Yes, NCT06843980 is actively recruiting participants. Contact the research team at rsweinstein@moximed.com for enrollment information.
Where is the NCT06843980 trial being conducted?
This trial is being conducted at Davis, United States, Oceanside, United States, Sacramento, United States, Chicago, United States and 5 additional locations.
Who is sponsoring the NCT06843980 clinical trial?
NCT06843980 is sponsored by Moximed. The principal investigator is Rose S Weinstein at Moximed. The trial plans to enroll 100 participants.