NCT07466966 Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis
| NCT ID | NCT07466966 |
| Status | Recruiting |
| Phase | — |
| Sponsor | St. Anne's University Hospital Brno, Czech Republic |
| Condition | Peri-implantitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 106 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2028-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 106 participants in total. It began in 2026-01-01 with a primary completion date of 2028-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This multicenter, single-masked randomized controlled clinical trial evaluates the effectiveness of minimally-invasive non-surgical therapy (MINST) compared with standard non-surgical peri-implant therapy (NSPT) in patients diagnosed with peri-implantitis. The study investigates clinical outcomes, radiographic bone levels, patient-reported outcomes, and treatment time over 12 months.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 * Peri-implantitis diagnosis (PPD \>6 mm, BOP+, bone loss ≥3 mm) * Accessible implant surface without removing suprastructure * FMPS \<30%, FMBS \<30-35% Exclusion Criteria: * Antibiotics in last 3 months * Pregnancy/lactation * Uncontrolled diabetes (HbA1c ≥7) * Long-term SPIC (\>2 years) * Previous implant therapy \<12 months * Smoking/vaping in last 12 months * Hopeless implant * Need for adjunctive antibiotics
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07466966 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Peri-implantitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07466966 currently recruiting?
Yes, NCT07466966 is actively recruiting participants. Contact the research team at filiphromcik@mail.muni.cz for enrollment information.
Where is the NCT07466966 trial being conducted?
This trial is being conducted at Brno, Czechia.
Who is sponsoring the NCT07466966 clinical trial?
NCT07466966 is sponsored by St. Anne's University Hospital Brno, Czech Republic. The trial plans to enroll 106 participants.