NCT06611878 Memory for Music: Individual Intensive Musical Training in Alzheimer's Disease
| NCT ID | NCT06611878 |
| Status | Recruiting |
| Phase | — |
| Sponsor | NORCE Norwegian Research Centre AS |
| Condition | Alzheimer Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 113 participants |
| Start Date | 2024-12-01 |
| Primary Completion | 2027-10-01 |
Trial Parameters
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
Brief Summary
This project, called Memory for Music, focuses on the increasing number of people worldwide living with dementia, especially Alzheimer's disease (AD). AD typically starts with memory problems and eventually affects daily activities. Active music interventions, especially singing, have shown positive effects on mood, behavior, and quality of life for people with dementia, but their impact on cognition is not well understood. The project aims to address this gap by studying the effects of learning new songs on cognitive, behavioral, and brain functioning. The study will involve home-dwelling adults aged 65 or older with AD from Argentina, Austria, and Norway. Participants will undergo 5 months of intensive musical training (twice a week) and 5 months of minimal training (once a month) in a random order, with a 2-month break in between. The interventions include learning new songs with a personal music teacher. General cognition will be measured using the Alzheimer's Disease Assessment Scale - Cognitive (ADAS-cog), and memory for music will be assessed through various methods, including behavioral tasks and brain responses (EEG). Mood will also be evaluated in each session. The goal is to include 113 participants to ensure reliable detection of meaningful effects. The study will explore how mood and memory for music contribute to changes in cognitive abilities, and whether these effects vary based on factors such as sex, age, AD stage, or previous musical training and general education. The project emphasizes collaboration between researchers, service providers, and users to ensure the study's relevance and applicability.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of Alzheimer's disease * Home-dwelling * Non-musician Exclusion Criteria: * Non-Alzheimer dementia * Living in care home * History as a professional musician
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.