NCT07546565 Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis
| NCT ID | NCT07546565 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Medical Center Ho Chi Minh City (UMC) |
| Condition | Colon Cancer |
| Study Type | INTERVENTIONAL |
| Enrollment | 74 participants |
| Start Date | 2025-09-01 |
| Primary Completion | 2027-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 74 participants in total. It began in 2025-09-01 with a primary completion date of 2027-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is a randomized controlled trial conducted at University Medical Center Ho Chi Minh City to evaluate the role of mechanical bowel preparation (MBP) in patients undergoing laparoscopic right hemicolectomy with totally intracorporeal anastomosis for colon cancer. Mechanical bowel preparation is commonly used before colorectal surgery to reduce bowel contents and potentially decrease the risk of postoperative infections. However, its benefit remains controversial, particularly in intracorporeal anastomosis, where intra-abdominal contamination may influence surgical outcomes. In this study, eligible patients will be randomly assigned to one of two groups: with or without mechanical bowel preparation before surgery. The study aims to compare intraoperative events, postoperative complications, and recovery outcomes between the two groups. The primary outcome is the rate of surgical site infection (SSI) within 30 days after surgery. Secondary outcomes include intraoperative fecal contamination, anastomotic leakage, postoperative ileus, operative time, and recovery parameters such as time to first bowel movement and length of hospital stay. The findings of this study are expected to clarify the role of mechanical bowel preparation in reducing postoperative infections and improving surgical outcomes in patients undergoing laparoscopic right hemicolectomy.
Eligibility Criteria
Inclusion Criteria: * Patients with colon cancer stage I-III according to the TNM classification * Patients undergoing elective right hemicolectomy or extended right hemicolectomy with totally intracorporeal anastomosis at University Medical Center Ho Chi Minh City * Postoperative histopathological confirmation of adenocarcinoma Exclusion Criteria: * Patients undergoing emergency surgery * Contraindications to mechanical bowel preparation (e.g., bowel obstruction, subobstruction, bowel perforation, or peritumoral abscess) * Contraindications to laparoscopic surgery (American Society of Anesthesiologists \[ASA\] physical status IV or V) or to intracorporeal anastomosis * Distant metastasis at the time of surgery (stage IV according to the TNM classification) * Recurrent colon cancer after prior surgery * Synchronous primary malignancies in other organs * Patients undergoing palliative surgery or surgery for tumor-related complications (non-curative intent) * Inability to complete follow-up or be contacted
Contact & Investigator
Tran D Huy, PhD, MD
PRINCIPAL INVESTIGATOR
University medical center HCMC
Frequently Asked Questions
Who can join the NCT07546565 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Colon Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07546565 currently recruiting?
Yes, NCT07546565 is actively recruiting participants. Contact the research team at huy.td@umc.edu.vn for enrollment information.
Where is the NCT07546565 trial being conducted?
This trial is being conducted at Ho Chi Minh City, Vietnam.
Who is sponsoring the NCT07546565 clinical trial?
NCT07546565 is sponsored by University Medical Center Ho Chi Minh City (UMC). The principal investigator is Tran D Huy, PhD, MD at University medical center HCMC. The trial plans to enroll 74 participants.
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