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Recruiting NCT04577599

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

Trial Parameters

Condition Lung Neoplasms
Sponsor Wake Forest University Health Sciences
Study Type INTERVENTIONAL
Phase N/A
Enrollment 1,160
Sex ALL
Min Age 40 Years
Max Age 54 Years
Start Date 2021-01-07
Completion 2028-10
Interventions
Mobile Low-dose Computed Tomography (LDCT) Screening

Brief Summary

Low-dose CT Screening has been shown in two large trials in the United States (NLST) and Europe (NELSON) to increase overall survival in subjects 55 years of age and older with a strong smoking history. Unfortunately, in both North Carolina (NC) and South Carolina (SC), subjects are found to have the above referenced smoking history prior to reaching the minimum age in these studies. This study is aimed at decreasing the minimum age of screening in a high-risk population.

Eligibility Criteria

Inclusion Criteria: * Subject must meet all the following applicable inclusion criteria to participate in this study: 1. Written informed consent and HIPAA authorization for release of personal health information. NOTE: HIPAA authorization may be included in the informed consent or obtained separately. 2. Age 40-54 years at the time of consent. 3. A positive smoking history of greater/equal to 30 pack years and they are either currently smoking or have quit within the last 15 years. 4. Ability to read and understand the English and/or Spanish language. 5. Ability to understand and comply with study procedures for the entire length of the study. Exclusion Criteria: * Subjects meeting any of the criteria below may not participate in the study: 1. Known diagnosis of lung cancer in the past 5 years. 2. Any known contraindication to having a low-dose CT Scan. 3. Known pregnancy.

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