NCT07607509 Lumbar Paravertebral Block vs Erector Spinae Plane Block in Elderly Patients Undergoing Lumbar Spine Surgery
| NCT ID | NCT07607509 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Poznan University of Medical Sciences |
| Condition | Spine Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2026-05-25 |
| Primary Completion | 2027-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2026-05-25 with a primary completion date of 2027-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective, randomized controlled trial aims to compare the analgesic efficacy of lumbar paravertebral block (L-PVB) and lumbar erector spinae plane block (L-ESPB) in elderly patients undergoing lumbar spine surgery. Effective postoperative pain management in this population is essential due to increased susceptibility to opioid-related adverse effects. Participants aged 65 years and older will be randomly assigned to receive either bilateral L-PVB or bilateral L-ESPB in addition to standardized general anesthesia. The primary objective is to evaluate differences in postoperative opioid consumption within the first 48 hours after surgery. Secondary outcomes include pain intensity, intraoperative opioid use, time to mobilization, length of hospital stay, and incidence of opioid-related adverse events.
Eligibility Criteria
Inclusion Criteria: * ge ≥65 years * Scheduled for elective lumbar spine surgery * American Society of Anesthesiologists (ASA) physical status I-III * Ability to assess pain using the Numeric Rating Scale (NRS) * Provision of written informed consent Exclusion Criteria: * Refusal to participate * Chronic opioid therapy * Coagulation disorders * Use of anticoagulant therapy contraindicating regional anesthesia * Infection at the planned needle insertion site * Allergy to ropivacaine or other study-related medications * Severe hepatic failure * Severe renal failure * Cognitive impairment preventing reliable pain assessment * Inability to cooperate with study procedures * Extensive reoperation or surgery of unusually large extent that may interfere with outcome assessment * Contraindications to general anesthesia or regional anesthesia
Contact & Investigator
Katarzyna Wieczorowska-Tobis, MD PhD
STUDY CHAIR
Poznan University of Medical Sciences
Frequently Asked Questions
Who can join the NCT07607509 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, up to 100 Years, studying Spine Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07607509 currently recruiting?
Yes, NCT07607509 is actively recruiting participants. Contact the research team at treysner@ump.edu.pl for enrollment information.
Where is the NCT07607509 trial being conducted?
This trial is being conducted at Poznan, Poland.
Who is sponsoring the NCT07607509 clinical trial?
NCT07607509 is sponsored by Poznan University of Medical Sciences. The principal investigator is Katarzyna Wieczorowska-Tobis, MD PhD at Poznan University of Medical Sciences. The trial plans to enroll 120 participants.