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Recruiting Phase 2 NCT07162181

Long-Term Safety of Pirtobrutinib in Participants With Previously Treated Types of Blood Cancers

Trial Parameters

Condition Lymphoma, Non-Hodgkin
Sponsor Eli Lilly and Company
Study Type INTERVENTIONAL
Phase Phase 2
Enrollment 13
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-08-07
Completion 2030-05
Interventions
Pirtobrutinib

Brief Summary

The purpose of this study is to find out more about the long-term safety of pirtobrutinib in participants with previously treated types of blood cancer. Participants must have chronic lymphocytic leukemia, small lymphocytic lymphoma, or non-Hodgkins lymphoma. The study is open to those who completed the original study - J2N-MC-JZNJ (NCT04849416) and continue to benefit from treatment. Treatment will be given every 12 weeks and this study is expected to last about 5 years.

Eligibility Criteria

Inclusion Criteria: * Currently enrolled and active in the originator study, JZNJ. A participant is considered active in the study if they are receiving study intervention * Agree to comply with contraception requirements. Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies Exclusion Criteria: * Are pregnant, or intend to become pregnant during the study, or within 30 days of last dose of study treatment or to breastfeed during the study or within 1 week of the last dose of study treatment

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