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b cell lymphoma

Total Trials
7
Recruiting Now
7
Trial Phases
Phase 3, Phase 1, Phase 2, Phase 1

Lymphoma trials span diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Hodgkin lymphoma, mantle cell lymphoma, and T-cell lymphomas β€” each with distinct biology and treatment response. CAR-T cell therapy has established a new standard in relapsed/refractory DLBCL, and trials now aim to move this approach earlier in the treatment sequence.

Active trials evaluate bispecific antibodies (mosunetuzumab, epcoritamab, glofitamab), next-generation CAR-T cell products (CD19/CD22 dual targets, BCMA-targeting), BTK inhibitors in B-cell lymphomas, and total metabolic volume on PET as a predictive biomarker for treatment adaptation.

Frequently Asked Questions — b cell lymphoma Clinical Trials

How many clinical trials are currently recruiting for b cell lymphoma?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for b cell lymphoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for b cell lymphoma?
b cell lymphoma research spans Phase 1 (4 trials), Phase 2 (3 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a b cell lymphoma clinical trial?
Eligibility criteria for b cell lymphoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
4
Phase 2
3
Phase 3
1
Top Sponsors
BeOne Medicines 1 trial
Uppsala University 1 trial
British Columbia Cancer Agency 1 trial
Jiangsu Topcel-KH Pharmaceutical Co., Ltd. 1 trial
Swiss Cancer Institute 1 trial

Recruiting Clinical Trials

NCT06742996 Phase 3
Recruiting
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
Enrollment
300 pts
Location
United States, Argen...
Sponsor
BeOne Medicines
View Trial →
NCT06002659 Phase 1, Phase 2
Recruiting
CAR20(NAP)-T Therapy for B Cell Lymphoma (CARMA-01 Study)
Enrollment
18 pts
Location
Sweden
Sponsor
Uppsala University
View Trial →
NCT06208735 Phase 1
Recruiting
CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
Enrollment
24 pts
Location
Canada
Sponsor
British Columbia Cancer Agency
View Trial →
NCT07369492 Phase 1
Recruiting
Safety and Efficacy Study of BAFF-R CAR-T Cells in Adult Subjects With CD19-Negative Relapsed or Refractory B-Cell Lymphoma
Enrollment
30 pts
Location
China
Sponsor
Jiangsu Topcel-KH Pharmaceutic...
View Trial →
NCT07593482 Phase 2
Recruiting
Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.
Enrollment
92 pts
Location
Switzerland
Sponsor
Swiss Cancer Institute
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NCT06566586 Phase 2
Recruiting
A Clinical Study to Evaluate the Efficacy and Safety of TQB3702 Tablets Combined With Immunochemotherapy for the Treatment of B-cell Lymphoma
Enrollment
80 pts
Location
China
Sponsor
Chia Tai Tianqing Pharmaceutic...
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NCT06976437 EARLY_Phase 1
Recruiting
A Clinical Study of Allogeneic CD19/BCMA CAR-T Cells for the Treatment of R/R B-cell Malignant Tumors
Enrollment
21 pts
Location
China
Sponsor
YANRU WANG
View Trial →

Related Conditions

mantle cell lymphoma (2) b cell leukemia (1) non hodgkin s lymphoma (1) b cell acute lymphoblastic leukemia (1) diffuse large b cell lymphoma (1) high grade b cell lymphoma (1) primary mediastinal large b cell lymphoma pmbcl (1) multiple myeloma (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology