NCT06832761 Lifestyle Intervention in the Memory Clinics of General and Academic Hospitals Trial
| NCT ID | NCT06832761 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Maastricht University Medical Center |
| Condition | Lifestyle Intervention |
| Study Type | INTERVENTIONAL |
| Enrollment | 300 participants |
| Start Date | 2025-01-27 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 300 participants in total. It began in 2025-01-27 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Lifestyle Intervention in the memory clinics of General and academic Hospitals Trial (LIGHT) is a multi-center, randomized, controlled, lifestyle intervention trial among 300 older adults (≥50 years) with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) at risk of dementia. Participants are randomized in a 1:1 ratio to Group A (tailored lifestyle intervention) or Group B (general health advice) for a duration of 12 months. The lifestyle intervention comprises three parts 1) Lifestyle coaching, 2) a voucher program, and 3) online self-management. Group B will receive general health advice.
Eligibility Criteria
Inclusion Criteria: * ≥50 years of age at pre-screening; * Having a diagnosis of SCD or MCI; * Presence of ≥ 2 modifiable risk factors for dementia. Exclusion Criteria: * Having a diagnosis of dementia; * Insufficient understanding of the Dutch language; * Conditions affecting safe and continuous engagement in the intervention (e.g. under treatment for current malignant diseases, major psychiatric disorders (e.g. major depression, psychosis, bipolar disorder), other conditions preventing co-operation as judged by the local study nurse or consulted physician at the local study site; * Participation in any other research intervention trial at time of pre-screening and throughout the study period.
Contact & Investigator
Sebastian Köhler, Professor
PRINCIPAL INVESTIGATOR
Maastricht University
Frequently Asked Questions
Who can join the NCT06832761 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, studying Lifestyle Intervention. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06832761 currently recruiting?
Yes, NCT06832761 is actively recruiting participants. Contact the research team at n.janssen@maastrichtuniversity.nl for enrollment information.
Where is the NCT06832761 trial being conducted?
This trial is being conducted at Amsterdam, Netherlands, Maastricht, Netherlands.
Who is sponsoring the NCT06832761 clinical trial?
NCT06832761 is sponsored by Maastricht University Medical Center. The principal investigator is Sebastian Köhler, Professor at Maastricht University. The trial plans to enroll 300 participants.