NCT06405750 Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
| NCT ID | NCT06405750 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital Bispebjerg and Frederiksberg |
| Condition | Atrial Fibrillation |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,000 participants |
| Start Date | 2024-08-01 |
| Primary Completion | 2035-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,000 participants in total. It began in 2024-08-01 with a primary completion date of 2035-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram. In connection with the operation, the small pouch known as the auricle of the heart is closed, which can be completely removed after closing. This procedure is common in patients with atrial fibrillation to protect the brain from stroke. In the project, all patients will have this auricle closed if they agree to participate in the project. After closure, the auricle is usually discarded. We will analyze the blood and the auricle tissue taken (if available) in connection with the operation itself, together with the analysis of the electrocardiogram recorded before the planned heart operation.
Eligibility Criteria
Inclusion Criteria: * signed informed consent AND * planned any open-heart surgery: * CABG * valve repair or replacement * aorta surgery * any combination of the above Exclusion Criteria: * current endocarditis * follow-up not possible
Contact & Investigator
Helena Dominguez
STUDY DIRECTOR
University Hospital Bispebjerg and Frederiksberg
Frequently Asked Questions
Who can join the NCT06405750 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Atrial Fibrillation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06405750 currently recruiting?
Yes, NCT06405750 is actively recruiting participants. Contact the research team at mdom0002@regionh.dk for enrollment information.
Where is the NCT06405750 trial being conducted?
This trial is being conducted at Copenhagen, Denmark.
Who is sponsoring the NCT06405750 clinical trial?
NCT06405750 is sponsored by University Hospital Bispebjerg and Frederiksberg. The principal investigator is Helena Dominguez at University Hospital Bispebjerg and Frederiksberg. The trial plans to enroll 1,000 participants.
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