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Recruiting Phase 4 NCT06782529

NCT06782529 Knee Injections for Obese Patients With Knee Arthritis

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Clinical Trial Summary
NCT ID NCT06782529
Status Recruiting
Phase Phase 4
Sponsor Mayo Clinic
Condition Osteoarthritis of Knee
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2025-01-24
Primary Completion 2027-01-24

Eligibility & Interventions

Sex All sexes
Min Age 55 Years
Max Age 85 Years
Study Type INTERVENTIONAL
Interventions
Triamcinolone Acetonide Low DoseTriamcinolone Acetonide Standard Dose

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 40 participants in total. It began in 2025-01-24 with a primary completion date of 2027-01-24.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to assess obese patients with knee arthritis and determine the non-inferiority of a low dose steroid treatment vs. standard dose steroid treatment for two knee outcome measures: pain and function.

Eligibility Criteria

Inclusion Criteria: • Patients with BMI ≥30 kg/m2 and radiograph-proven knee osteoarthritis who are interested in receiving a steroid injection for knee arthritis. Exclusion Criteria: * BMI \< 30 kg/m2 * Uncontrolled diabetics with a hemoglobin A1c \> 8% * No other treatment within the time frame of the study. * Patients that are undergoing physical therapy at the time of the study.

Contact & Investigator

Central Contact

Jeffrey P Nadwodny, DO

✉ nadwodny.jeffrey@mayo.edu

📞 904 953 6722

Principal Investigator

Jeffrey P Nadwodny, DO

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT06782529 clinical trial?

This trial is open to participants of all sexes, aged 55 Years or older, up to 85 Years, studying Osteoarthritis of Knee. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06782529 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT06782529 currently recruiting?

Yes, NCT06782529 is actively recruiting participants. Contact the research team at nadwodny.jeffrey@mayo.edu for enrollment information.

Where is the NCT06782529 trial being conducted?

This trial is being conducted at Jacksonville, United States.

Who is sponsoring the NCT06782529 clinical trial?

NCT06782529 is sponsored by Mayo Clinic. The principal investigator is Jeffrey P Nadwodny, DO at Mayo Clinic. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology