NCT06820125 Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation
| NCT ID | NCT06820125 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universita di Verona |
| Condition | Rehabilitation |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2023-07-05 |
| Primary Completion | 2023-07-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2023-07-05 with a primary completion date of 2023-07-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The first aim of this project is to investigate the effects of different high-tech neurorehabilitation interventions (cognitive, motor, and combined cognitive-motor) on both cognitive and motor disability outcomes in people with multiple sclerosis (MS). The second aim is to identify the cognitive and motor profiles of MS patients who benefit the most from either the combined cognitive-motor rehabilitation intervention or the isolated cognitive or motor treatments.
Eligibility Criteria
Inclusion Criteria: * presence of mild (one or two neuropsychological tests below the cut-off score, 5th percentile) or severe (more than two neuropsychological tests below the cut-off score, 5th percentile) cognitive impairment, * mild to moderate walking disability with Expanded Disability Status Scale (EDSS) between 3 and 6, * no relapse or associated steroid use in the past three months, * adequate visual and auditory capacity to operate computer software. Exclusion Criteria: * presence of other neurological disorders than MS, * major psychiatric disorders, * high levels of anxiety and/or depression (score\>20 for Depression scale and up to 14 for Anxiety scale on Italian adaptation of the Depression, Anxiety and Stress Scale (DASS-21), * substance abuse, * any type of rehabilitation intervention in the month prior to recruitment * pharmacological therapy not well defined and/or changed during the study * presence of paroxysmal vertigo * lower limb botulinum toxin injections within the previous 12 weeks
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06820125 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Rehabilitation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06820125 currently recruiting?
Yes, NCT06820125 is actively recruiting participants. Contact the research team at valentina.varalta@univr.it for enrollment information.
Where is the NCT06820125 trial being conducted?
This trial is being conducted at Verona, Italy.
Who is sponsoring the NCT06820125 clinical trial?
NCT06820125 is sponsored by Universita di Verona. The trial plans to enroll 48 participants.