NCT04232566 Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
| NCT ID | NCT04232566 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | Obesity, Morbid |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2022-02-20 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2022-02-20 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin resistance.
Eligibility Criteria
Inclusion Criteria: * Undergoing gastric bypass surgery * Confirmed AUROC F=0 or F\>2 liver fibrosis * Age 30-70 years * BMI greater than 40 kg/m2 * Negative pregnancy test (female only) * Lab Values: Normal TSH Exclusion Criteria: * Autoimmune diseases * Hepatitis B or C positive * Heavy alcohol use * Active smoking history * Active cancer history * History of asthma * History of COPD * Taking Plavix or Coumadin * Blood donation within past 2 months * Glucocorticoid Therapy * Taking antihistamine on regular basis
Contact & Investigator
Elena Anna O De Filippis
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT04232566 clinical trial?
This trial is open to participants of all sexes, aged 30 Years or older, up to 70 Years, studying Obesity, Morbid. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04232566 currently recruiting?
Yes, NCT04232566 is actively recruiting participants. Contact the research team at stewart.keegan@mayo.edu for enrollment information.
Where is the NCT04232566 trial being conducted?
This trial is being conducted at Scottsdale, United States.
Who is sponsoring the NCT04232566 clinical trial?
NCT04232566 is sponsored by Mayo Clinic. The principal investigator is Elena Anna O De Filippis at Mayo Clinic. The trial plans to enroll 60 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.