NCT07475936 Intravenous Tenecteplase in Very Old Patients With Acute Ischemic Stroke
| NCT ID | NCT07475936 |
| Status | Recruiting |
| Phase | — |
| Sponsor | First Affiliated Hospital of Guangxi Medical University |
| Condition | Acute Ischemic Stroke |
| Study Type | OBSERVATIONAL |
| Enrollment | 392 participants |
| Start Date | 2026-03-22 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 392 participants in total. It began in 2026-03-22 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The benefit of intravenous tenecteplase in very old patients with acute ischemic stroke (AIS) remain uncertain. This real-world study aims to evaluate the effectiveness and safety of intravenous tenecteplase in AIS patients aged 80 years or older within 4.5 hours of symptom onset.
Eligibility Criteria
Inclusion Criteria: 1. Age \> 80 years; 2. Clinically diagnosed with acute ischemic stroke and arrived at the hospital within 4.5 hours of symptom onset; 3. Informed consent signed by the patient or legally authorized representative. Exclusion Criteria: 1. Any contraindication to intravenous thrombolysis (excluding age); 2. Previous treatment with other thrombolytic agents such as alteplase, urokinase, plasminogen activator, or reteplase; 3. Current participation in other interventional studies; 4. The investigator deems the patient unsuitable for this study or the study might pose significant risk to the patient (e.g., due to psychiatric disorders, cognitive or emotional impairments that prevent understanding or adherence to study procedures and/or follow-up).
Contact & Investigator
Yuan Wu, MD, PhD
PRINCIPAL INVESTIGATOR
First Affiliated Hospital of Guangxi Medical University
Frequently Asked Questions
Who can join the NCT07475936 clinical trial?
This trial is open to participants of all sexes, aged 80 Years or older, studying Acute Ischemic Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07475936 currently recruiting?
Yes, NCT07475936 is actively recruiting participants. Contact the research team at dongpan012@hotmail.com for enrollment information.
Where is the NCT07475936 trial being conducted?
This trial is being conducted at Nanning, China.
Who is sponsoring the NCT07475936 clinical trial?
NCT07475936 is sponsored by First Affiliated Hospital of Guangxi Medical University. The principal investigator is Yuan Wu, MD, PhD at First Affiliated Hospital of Guangxi Medical University. The trial plans to enroll 392 participants.
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