Inspiratory Muscle Training in Obese Breast Cancer Survivors
This study tests whether special breathing exercises that strengthen the muscles you use to breathe in can help obese breast cancer survivors exercise more comfortably and for longer periods. Researchers will compare women who do this inspiratory muscle training to those who don't to see if it improves their ability to be physically active.
Key Objective: The trial is testing whether inspiratory muscle training can improve exercise tolerance and physical fitness in obese breast cancer survivors.
Who to Consider: Obese women who have been treated for stage 0-III breast cancer and are interested in improving their exercise capacity should consider enrolling.
Trial Parameters
Brief Summary
The investigators propose a randomized controlled trial to determine the effectiveness of inspiratory muscle training in improving exercise tolerance among stage 0-III obese breast cancer survivors.
Eligibility Criteria
Inclusion Criteria: * completed active treatment for a Stage 0-III breast cancer diagnosis within 6 months to 5 years of enrollment. * obese as defined by a body mass index (BMI) of 30 to 50 kg/m2 * patients who are on adjuvant endocrine therapy will be allowed to participate. * sedentary (participating in less than 90 min of moderate intensity activity per week) and have at least one limitation in activity on the 10-question RAND-36 Physical Function Subscale to ensure some exercise intolerance Exclusion Criteria: * functional limitations that make independent exercise unsafe * metastatic breast cancer * ongoing or active infection with recent antibiotics or steroids * Bilateral Axillary lymph node dissection (ALND) of \>5 lymph nodes on each side, which could increase risk of lymphadenopathy with repeated blood pressure measurements during exercise or if patient has been advised by their clinician to avoid repeated BP measures on both arms. Bilateral Sentinel Lymph Node Biopsy (SLNB)