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Recruiting NCT05459636

NCT05459636 Inspiratory Muscle Strength Training in Adults With Obesity

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Clinical Trial Summary
NCT ID NCT05459636
Status Recruiting
Phase
Sponsor Florida State University
Condition Obesity
Study Type INTERVENTIONAL
Enrollment 44 participants
Start Date 2023-12-07
Primary Completion 2027-06-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 45 Years
Study Type INTERVENTIONAL
Interventions
High-resistance inspiratory muscle strength trainingVery-low-resistance inspiratory muscle strength training

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 44 participants in total. It began in 2023-12-07 with a primary completion date of 2027-06-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to determine whether inspiratory muscle strength training reduces blood pressure in adults with obesity.

Eligibility Criteria

Inclusion Criteria: \- Body mass index 30 - 40 kg/m2 Exclusion Criteria: * Not weight stable (\<5% change in body mass over the past six months) * Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus) * Current, or history of uncontrolled, Stage 2 hypertension (blood pressure \>140 / 90 mmHg; anti-hypertensive medications are permitted) * Diagnosed obstructive sleep apnea * Previous bariatric surgery * Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s) * Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping) * Pregnant (self-reported and confirmed via urine pregnancy test), lactating (self-reported), or post-menopausal (self-reported) females * Prisoners * Per the POWERbreathe® company: * Patients who have undergone recent abdominal surgery and those with abdominal hernia. * Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnea. * If a patient is suffering from a ruptured eardrum or any other condition of the ear. * Patients with marked elevated left ventricular end-diastolic volume and pressure. * Patients with worsening heart failure signs and symptoms after training. * If an individual is suffering from a cold, sinusitis or respiratory tract infection, it is advised that they do not use the POWERbreathe device.

Contact & Investigator

Central Contact

Joseph C Watso, PhD

✉ jwatso@fsu.edu

📞 850-644-5260

Frequently Asked Questions

Who can join the NCT05459636 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05459636 currently recruiting?

Yes, NCT05459636 is actively recruiting participants. Contact the research team at jwatso@fsu.edu for enrollment information.

Where is the NCT05459636 trial being conducted?

This trial is being conducted at Tallahassee, United States.

Who is sponsoring the NCT05459636 clinical trial?

NCT05459636 is sponsored by Florida State University. The trial plans to enroll 44 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology