NCT06600100 Inhibitory Control Training for Excess Weight: Behavioural, Cognitive and Anthropometric Changes
| NCT ID | NCT06600100 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Raquel Vilar López |
| Condition | Overweight and Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 54 participants |
| Start Date | 2024-11-30 |
| Primary Completion | 2026-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 54 participants in total. It began in 2024-11-30 with a primary completion date of 2026-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
People with excess weight (EW) are characterized by high impulsivity, high levels of craving for high-calorie foods, deficits in inhibitory control, and maladaptive decision-making. The proposed intervention seeks to target these issues. Thus, the present study aims to determine the effectiveness of combining inhibitory control training with usual treatment (diet and physical exercise) in treating people with EW to produce cognitive, behavioral and anthropometric changes. Participants will be randomly allocated to one of two groups: 1) the experimental group that would receive active inhibitory control training and (2) the active control group that will receive placebo inhibitory control training. Both groups will receive individualized diet and physical exercise guidelines. Training requires to inhibit responding to certain foods presented during computerized tasks. Using a food Go/No-Go paradigm, individuals are asked to press a button when a Go cue is presented next to an image and to refrain from pressing a button when a No-Go cue (e.g., a bold frame) is presented. In the experimental group, pictures of healthy and unhealthy foods are always paired with the Go and the No-Go signal, respectively whereas in the control group healthy and unhealthy foods are paired 50% of the time with the Go and 50% with the No-Go signal. It is hypothesized that the experimental intervention would be effective improving (i) Body Mass Index (BMI), (ii) food craving, (iii) anthropometric measures (waist circumference and waist-to-hip and waist-to-height ratios), (iv) eating and physical exercise behaviors (decreased caloric intake and increased frequency and time of physical activity), (v) emotional symptoms and emotional eating (depression, anxiety, emotional regulation, emotional eating, reward-related eating, non-homeostatic eating), and (vi) cognitive abilities (motor and cognitive inhibition, delay of gratification, impulsivity, working memory, cognitive flexibility and decision making).
Eligibility Criteria
Inclusion Criteria: * BMI between 25 and 39.9 * Age between 18 and 60 years * Proficiency in the Spanish language * Internet access * Computer and smartphone Exclusion Criteria: * Traumatic, digestive, metabolic or systemic disorders that affect the central nervous system, autonomic or endocrine * Severe psychopathological disorders, moderate depressive symptoms or treatment for depression * Eating disorders
Contact & Investigator
Raquel Vilar López, Ph.D
PRINCIPAL INVESTIGATOR
Universidad de Granada
Frequently Asked Questions
Who can join the NCT06600100 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Overweight and Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06600100 currently recruiting?
Yes, NCT06600100 is actively recruiting participants. Contact the research team at rvilar@ugr.es for enrollment information.
Where is the NCT06600100 trial being conducted?
This trial is being conducted at Granada, Spain.
Who is sponsoring the NCT06600100 clinical trial?
NCT06600100 is sponsored by Raquel Vilar López. The principal investigator is Raquel Vilar López, Ph.D at Universidad de Granada. The trial plans to enroll 54 participants.
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