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Recruiting NCT05428358

NCT05428358 Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery

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Clinical Trial Summary
NCT ID NCT05428358
Status Recruiting
Phase
Sponsor University of Aarhus
Condition Pancreatic Cancer
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2022-08-30
Primary Completion 2027-12-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 99 Years
Study Type INTERVENTIONAL
Interventions
Preoperative MRI

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 200 participants in total. It began in 2022-08-30 with a primary completion date of 2027-12-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of the study is to examine the incremental value of using magnetic resonance imaging (MRI) in addition to computed tomography (CT) in the diagnostic workup of pancreatic cancer patients.

Eligibility Criteria

Inclusion criteria: * Pancreatic cancer patients considered to have a locally resectable or borderline resectable tumor by the local hepato-pancreato-biliary multidisciplinary team board * No liver metastases on CT * At least 18 years old and able to provide informed consent * Expected pancreatic ductal adenocarcinoma based on CT scan Exclusion criteria: * Metastatic disease * Prior receipt of neoadjuvant chemotherapy or downstaging/-sizing treatment * Comorbidity rendering major surgery unfeasible (inoperable) * No informed consent * Unable to undergo MRI (Kidney insufficiency (eGFR \< 60 ml/min/1.73 m2 body surface ar-ea); Claustrophobia; Cardiac pacemaker) * Postoperative histology other than adenocarcinoma of pancreato-biliary origin. * MRI with liver-specific contrast performed during standard workup.

Contact & Investigator

Central Contact

Jakob Kirkegård, MD, PhD

✉ jakob.kirkegaard@auh.rm.dk

📞 +4522900604

Principal Investigator

Frank Mortensen, MD, DMSc

STUDY CHAIR

Aarhus University Hospital

Frequently Asked Questions

Who can join the NCT05428358 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Pancreatic Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05428358 currently recruiting?

Yes, NCT05428358 is actively recruiting participants. Contact the research team at jakob.kirkegaard@auh.rm.dk for enrollment information.

Where is the NCT05428358 trial being conducted?

This trial is being conducted at Aalborg, Denmark, Aarhus, Denmark, Copenhagen, Denmark.

Who is sponsoring the NCT05428358 clinical trial?

NCT05428358 is sponsored by University of Aarhus. The principal investigator is Frank Mortensen, MD, DMSc at Aarhus University Hospital. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology