Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation
Trial Parameters
Brief Summary
Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).
Eligibility Criteria
Inclusion Criteria: 1. Fluent in English and able to volunteer in the informed consent process and provide spontaneous narrative description of key elements, risks, and benefits of the study. 2. Aged 14 years to 18 years, inclusive. 3. Diagnosis of MDD based on psychologist diagnosis and DSM-5-checklist based interview. 4. Symptoms of moderate to severe depression according to Hamilton Depression Rating Scale Score \> 20. 5. Participants are not required to discontinue current interventions Exclusion Criteria: 1. Participation in an investigational drug trial within the past three months. 2. Contraindications to Transcranial Magnetic Stimulation including, but not limited to, a history of epilepsy, the presence of metallic foreign bodies, or implanted medical devices (e.g. ventriculoperitoneal shunt, pacemaker, medical pump). 3. Actively psychotic (i.e. disorganized, delusional, paranoid, or having hallucinations) 4. Actively suicidal (have a suicidal plan and intent and is on 1:1 clos