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Medical Condition
major depressive disorder mdd
Total Trials
8
Recruiting Now
8
Trial Phases
Phase 2, Phase 4
ClinicalMetric tracks all active clinical trials for major depressive disorder mdd sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.
Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.
Frequently Asked Questions — major depressive disorder mdd Clinical Trials
How many clinical trials are currently recruiting for major depressive disorder mdd?
ClinicalMetric currently tracks 8 actively recruiting clinical trials for major depressive disorder mdd, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for major depressive disorder mdd?
major depressive disorder mdd research spans Phase 2 (2 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a major depressive disorder mdd clinical trial?
Eligibility criteria for major depressive disorder mdd trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2 2
Phase 4 1
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT06773949
Recruiting
Enrollment
20 pts
Location
Canada
Sponsor
The Royal Ottawa Mental Health...
NCT07217444
Recruiting
Enrollment
60 pts
Location
United States
Sponsor
Children's Hospital Medical Ce...
NCT06782724 Phase 2
Recruiting
Enrollment
108 pts
Location
Czechia, Denmark, Ne...
Sponsor
University Medical Center Gron...
NCT06804525
Recruiting
Enrollment
2,500 pts
Location
Hong Kong
Sponsor
The University of Hong Kong
NCT07247344
Recruiting
Enrollment
1,000 pts
Location
China
Sponsor
Jiangsu Province Nanjing Brain...
NCT06843187 Phase 2
Recruiting
Enrollment
30 pts
Location
Canada
Sponsor
Unity Health Toronto
NCT07076342 Phase 4
Recruiting
Enrollment
42 pts
Location
United States
Sponsor
Stony Brook University
NCT06972368
Recruiting
Enrollment
60 pts
Location
Canada
Sponsor
Ciusss de L'Est de l'Île de Mo...
Related Conditions
suicidal ideation (2) treatment resistant depression trd (1) hospitalization in children (1) copd chronic obstructive pulmonary disease (1) als amyotrophic lateral sclerosis (1) ms multiple sclerosis (1) atypical parkinson disease (1) major depressive episode mde (1) persistent depressive disorder pdd (1) suicidal plan (1) suicidal attempt (1) suicidal gesture (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology