Improving Measurement and Treatment of Post-stroke Neglect
Trial Parameters
Brief Summary
This study examines how to best assess and treat post-stroke neglect. This study will examine the preliminary effects of an innovative intervention (repetitive task-specific practice + transcranial direct current stimulation) for individuals with neglect. This study will also determine whether items from various neglect assessments can be combined to establish a more comprehensive neglect measure.
Eligibility Criteria
Inclusion Criteria: * Ischemic or hemorrhagic stroke 3 months post stroke. * Fugl-Meyer Upper Extremity (FMA-Upper Extremity) score between 20-56/60 * Inducible motor evoked potential (MEP) of the abductor pollicis brevis (APB) on the paretic stimulation (TMS) * Demonstrate the presence of unilateral neglect (Virtual Reality Lateralized Attention Test score \<18) Exclusion Criteria: * History of cortical hemorrhagic stroke * Presence of any MRI, TMS, tDCS risk factors including: * history of seizures * history of brain tumor * hardware in skull or spine (e.g. coils, clips) * implantable medical device (e.g. pacemaker) * metal in body (not compatible with MRI) * pregnancy * Severe spasticity (Modified Ashworth Scale score 3) * Severe aphasia or cognitive impairment limiting participants' comprehension (National Institutes of Health Stroke Scale Level of Consciousness Commands Item score 1 or Best Language Item score 2) * Unable to travel to UE Motor Function Laboratory at the Center for