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RecruitingNCT06953375

Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty

Trial Parameters

ConditionTotal Knee Arthroplasty
SponsorUniversity of Colorado, Denver
Study TypeINTERVENTIONAL
PhaseN/A
Enrollment3,250
SexALL
Min Age18 Years
Max AgeN/A
Start Date2025-05-12
Completion2029-04
Interventions
NMESUsual Care

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Brief Summary

Patients experience dramatic quadriceps strength loss after total knee replacement, which contributes to persistent weakness and reduced long-term function after surgery. Neuromuscular electrical stimulation (NMES) reduces quadriceps weakness and improves patient function after knee replacement, but it is drastically underused in rehabilitation practice. This randomized trial will examine the effectiveness and feasibility of a comprehensive strategy for implementing neuromuscular electrical stimulation after knee replacement in two large healthcare organizations.

Eligibility Criteria

Inclusion Criteria: Site Inclusion Criteria: • UCHealth or Intermountain Health outpatient physical therapy clinic Patient Inclusion Criteria: * Underwent primary unilateral TKA * Attended outpatient rehabilitation at a participating clinic within 5 days after TKA * Attended at least 3 total outpatient physical therapy visits in total Exclusion Criteria: Patient Exclusion Criteria: * NMES Contraindications \[Patients with implanted cardiovascular cardiovertedefibrillator (ICD), active cancer, post-operative diagnosed deep vein thrombosis (DVT) in involved lower extremity\] * Previous lower extremity arthroplasty less than 12 weeks prior to scheduled TKA surgical date

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