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Recruiting NCT07324694

NCT07324694 Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery

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Clinical Trial Summary
NCT ID NCT07324694
Status Recruiting
Phase
Sponsor Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Condition Cardiac Surgery
Study Type OBSERVATIONAL
Enrollment 230 participants
Start Date 2025-04-26
Primary Completion 2026-01-20

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 230 participants in total. It began in 2025-04-26 with a primary completion date of 2026-01-20.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Intraoperative hemodynamic instability (IOHI) is a common occurrence during cardiac surgery and is associated with organ hypoperfusion. However, the specific impact of IOHI on composite adverse outcomes remains unclear. This prospective cohort study aims to evaluate the association between intraoperative hemodynamic instability (defined as MAP \< 65 mmHg or vasopressor requirement) and major postoperative complications (Delirium, Acute Kidney Injury, Stroke, or Mortality) in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass.

Eligibility Criteria

Inclusion Criteria: * Patients aged 18 years or older. * Scheduled for elective cardiac surgery (CABG, Valve replacement/repair, or combined procedures). * Surgery performed under cardiopulmonary bypass (CPB). * Preoperative sinus rhythm. * Signed informed consent form. Exclusion Criteria: * Emergency or salvage surgery. * Off-pump coronary artery bypass grafting. * Preoperative mechanical circulatory support (IABP, ECMO) requirement. * Pre-existing chronic renal failure requiring dialysis (HD/PD). * Pre-existing cognitive impairment, dementia, or history of psychiatric disorders affecting cooperation. * Pregnancy.

Contact & Investigator

Central Contact

Osman Uzundere, M.D.

✉ osmanuzundere@gmail.com

📞 +905330206362

Frequently Asked Questions

Who can join the NCT07324694 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Cardiac Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07324694 currently recruiting?

Yes, NCT07324694 is actively recruiting participants. Contact the research team at osmanuzundere@gmail.com for enrollment information.

Where is the NCT07324694 trial being conducted?

This trial is being conducted at Diyarbakır, Turkey (Türkiye).

Who is sponsoring the NCT07324694 clinical trial?

NCT07324694 is sponsored by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital. The trial plans to enroll 230 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology