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Recruiting NCT07425249

Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients

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Trial Parameters

Condition Postoperative Ileus
Sponsor Khyber Medical University Peshawar
Study Type INTERVENTIONAL
Phase N/A
Enrollment 96
Sex ALL
Min Age 17 Years
Max Age 85 Years
Start Date 2026-01-01
Completion 2026-08-25
Interventions
Chewing Gum

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Brief Summary

Postoperative ileus (POI) is a frequent complication after abdominal surgery, leading to delayed gastrointestinal motility, prolonged hospital stay, and increased patient discomfort. Chewing gum, as a form of sham feeding, has been proposed to stimulate gut motility through vagal stimulation and increased gastrointestinal secretions. This randomized controlled trial aims to assess the effect of chewing gum on early recovery of gastrointestinal motility in patients undergoing open gastrointestinal surgery.

Eligibility Criteria

Inclusion Criteria: * Age between 17 and 85 years. * Patients of either gender. * Undergoing open gastrointestinal surgical procedures (elective or emergency). * Willing to participate and able to provide informed consent. Exclusion Criteria: * Patients with metabolic or endocrine disorders (diabetes mellitus, hypothyroidism, or hyperthyroidism). * Patients with renal disease or electrolyte imbalance. * Patients with chronic constipation or neuromuscular disorders. * Patients with substance abuse or drug addiction. * Patients receiving medications affecting gut motility (calcium channel blockers or antiepileptic drugs). * Patients with dental prosthesis or undergoing laparoscopic gastrointestinal surgery.

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