NCT05654649 Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section
| NCT ID | NCT05654649 |
| Status | Recruiting |
| Phase | Phase 1, Phase 2 |
| Sponsor | Assiut University |
| Condition | Postoperative Ileus |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2022-12-01 |
| Primary Completion | 2024-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.
This trial targets 90 participants in total. It began in 2022-12-01 with a primary completion date of 2024-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Postoperative ileus is a perplexing problem for clinical surgeons. It occurs not only after abdominal surgery but also after any surgery that requires general anesthesia. Postoperative ileus is defined as the dysfunction of gastrointestinal motility after surgery, characterized by a decrease in, or stagnation of, intestinal peristalsis.
Eligibility Criteria
Inclusion Criteria: * •All participants will sign an informed consent prior to inclusion in the study. * All patients 18-40 years of full-term singleton pregnancy (37-41 weeks)., * American Society of Anaesthesiologists (ASA) classification class I and II scheduled. * for elective or semi-elective surgery (category 3 and 4 Caesarean sections). * All patients under spinal anesthesia for a Single baby pregnancy of more than 32 weeks will be included in this study. Exclusion Criteria: * will be patients' height \< 150 or \> 180 cm. * Body mass index (BMI) \>35 kg m-2. * Contraindication or refusal to undergo regional anesthesia. * any cardiovascular disease including arrhythmias and severe stenotic valvular heart disease.any renal or hepatic diseased patients.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05654649 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 40 Years, studying Postoperative Ileus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT05654649 trial and what does that mean for participants?
Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.
Is NCT05654649 currently recruiting?
Yes, NCT05654649 is actively recruiting participants. Contact the research team at ghadafadl77@gmail.com for enrollment information.
Where is the NCT05654649 trial being conducted?
This trial is being conducted at Asyut, Egypt.
Who is sponsoring the NCT05654649 clinical trial?
NCT05654649 is sponsored by Assiut University. The trial plans to enroll 90 participants.