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Recruiting NCT07366593

NCT07366593 Immune Profile and Respiratory Parameters in Down Syndrome Children With Acute Pneumonia: Pre-Intervention Analysis

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Clinical Trial Summary
NCT ID NCT07366593
Status Recruiting
Phase —
Sponsor Badr University
Condition Down Syndrome
Study Type OBSERVATIONAL
Enrollment 40 participants
Start Date 2025-07-01
Primary Completion 2026-01-30

Trial Parameters

Condition Down Syndrome
Sponsor Badr University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 40
Sex ALL
Min Age 1 Year
Max Age 6 Years
Start Date 2025-07-01
Completion 2026-01-30
Interventions
Pearson or Spearman correlations were used to assess relationships between immune and respiratory variables, and with age

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Brief Summary

Baseline serum IgG, IgA, IgM (nephelometry), total WBC count (automated analyzer), RR (manual count), and SaO2 (pulse oximetry) were measured. Pearson or Spearman correlations were used to assess relationships between immune and respiratory variables, and with age

Eligibility Criteria

Inclusion Criteria: * Down Syndrome with acute bronchopneumonia * sufficient cognitive ability Exclusion Criteria: * severe congenital heart defects * primary immunodeficiencies

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