NCT06322719 Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU
| NCT ID | NCT06322719 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hospital Clinico Universitario de Santiago |
| Condition | Acute Respiratory Failure |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,036 participants |
| Start Date | 2024-05-01 |
| Primary Completion | 2026-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,036 participants in total. It began in 2024-05-01 with a primary completion date of 2026-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Tracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications. Videolaryngoscopes (VLs) devices have been proposed to improve airway management, and the use of VLs are recommended as first-line or after a first-attempt failure using direct laryngoscopy in ICU airway management algorithms. Although until relatively few years ago there were doubts about whether videolaryngoscopes had advantages over direct laryngoscopy for endotracheal intubation (ETI) in critically ill patients, two recent studies (DEVICE (1), INTUBATE (2)), and a Cochrane review (3) have confirmed that videolaryn should be used?, and what is the best blade? . There are two types of blades commonly used with videolaryngoscopes: the "Macintosh" blade with a slight curvature, and hyperangulated blades. The "Macintosh" blades have a lower angle of vision, but they have the advantage of being similar to the blades commonly used in direct laryngoscopy, making them easy to use for the person performing the ETI. Hyperangulated blades have a greater angle of vision, improving glottic visualization, especially in patients with an anterior glottis. However, the need to overcome this angulation could potentially hinder the passage of the endotracheal tube to the vocal cords. It is unknown if either blade has any advantage for intubating critically ill patients.
Eligibility Criteria
Inclusion Criteria: * Age 18 years or older. * Admitted to an Intensive Care Unit. * Need for tracheal intubation during the stay in the ICU. * The device to be used for intubation is a videolaryngoscope Exclusion Criteria: * Pregnancy or lactation. * Emergent tracheal intubation that does not allow for the randomization of the procedure. * Need for tracheal intubation with a device other than the videolaryngoscope (fiberoptic bronchoscope, direct laryngoscopy, tracheostomy, etc.). * Tracheal intubation performed outside the ICU (Emergency Department, Hospital ward, etc.).
Contact & Investigator
Manuel Taboada, Ph.D.
PRINCIPAL INVESTIGATOR
University Clinical Hospital of Santiago de Compostela
Frequently Asked Questions
Who can join the NCT06322719 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Acute Respiratory Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06322719 currently recruiting?
Yes, NCT06322719 is actively recruiting participants. Contact the research team at manutabo@yahoo.es for enrollment information.
Where is the NCT06322719 trial being conducted?
This trial is being conducted at Santiago de Compostela, Spain, A Coruña, Spain, Albacete, Spain, Barcelona, Spain and 11 additional locations.
Who is sponsoring the NCT06322719 clinical trial?
NCT06322719 is sponsored by Hospital Clinico Universitario de Santiago. The principal investigator is Manuel Taboada, Ph.D. at University Clinical Hospital of Santiago de Compostela. The trial plans to enroll 1,036 participants.