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Recruiting NCT05193968

NCT05193968 Hot Flashes and Neurovascular Function in Women

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Clinical Trial Summary
NCT ID NCT05193968
Status Recruiting
Phase
Sponsor Mayo Clinic
Condition Hot Flashes
Study Type INTERVENTIONAL
Enrollment 120 participants
Start Date 2022-02-24
Primary Completion 2026-12

Eligibility & Interventions

Sex Female only
Min Age 40 Years
Max Age 60 Years
Study Type INTERVENTIONAL
Interventions
Sympathoexcitatory stressorsSodium NitroprussideAcetylcholine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 120 participants in total. It began in 2022-02-24 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship. As such, these studies are designed to provide a major step forward in understanding the link between hot flashes and neurovascular dysfunction and, by extension, cardiovascular disease in women.

Eligibility Criteria

Inclusion Criteria: * Non-smokers. * Non-obese. * Have at least one ovary. * Free from cardiovascular disease. * Not taking medications influencing cardiovascular function. Exclusion Criteria: \- None.

Contact & Investigator

Central Contact

Pamela A Engrav

✉ engrav.pamela@mayo.edu

📞 507-255-6938

Principal Investigator

Sarah Baker, PhD

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT05193968 clinical trial?

This trial is open to female participants only, aged 40 Years or older, up to 60 Years, studying Hot Flashes. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05193968 currently recruiting?

Yes, NCT05193968 is actively recruiting participants. Contact the research team at engrav.pamela@mayo.edu for enrollment information.

Where is the NCT05193968 trial being conducted?

This trial is being conducted at Rochester, United States.

Who is sponsoring the NCT05193968 clinical trial?

NCT05193968 is sponsored by Mayo Clinic. The principal investigator is Sarah Baker, PhD at Mayo Clinic. The trial plans to enroll 120 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology