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Recruiting NCT06972719

NCT06972719 Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy

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Clinical Trial Summary
NCT ID NCT06972719
Status Recruiting
Phase
Sponsor Duke University
Condition BRCA1 Mutation
Study Type INTERVENTIONAL
Enrollment 50 participants
Start Date 2025-09-30
Primary Completion 2026-12-31

Eligibility & Interventions

Sex Female only
Min Age 19 Years
Max Age 50 Years
Study Type INTERVENTIONAL
Interventions
Experimental ArmSOC Arm

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 50 participants in total. It began in 2025-09-30 with a primary completion date of 2026-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this study is to develop an educational aid about hormone replacement therapy that physicians can share with patients as part of their pre-surgical counseling for a risk-reducing salpingo-oophorectomy (RRSO).

Eligibility Criteria

Inclusion Criteria: * BRCA1 or BRCA2 germline mutation * scheduled for a risk-reducing salpingo-oophorectomy (RRSO) by Duke Gynecologic Oncologist * premenopausal Exclusion Criteria: * personal history of cancer * postmenopausal * \>50 years old * unable to provide informed consent in English

Contact & Investigator

Central Contact

Amelia Scott

✉ amelia.lorenzo@duke.edu

📞 (919) 613-4584

Principal Investigator

Laura Havrilesky

PRINCIPAL INVESTIGATOR

Duke University

Frequently Asked Questions

Who can join the NCT06972719 clinical trial?

This trial is open to female participants only, aged 19 Years or older, up to 50 Years, studying BRCA1 Mutation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06972719 currently recruiting?

Yes, NCT06972719 is actively recruiting participants. Contact the research team at amelia.lorenzo@duke.edu for enrollment information.

Where is the NCT06972719 trial being conducted?

This trial is being conducted at Chapel Hill, United States, Durham, United States.

Who is sponsoring the NCT06972719 clinical trial?

NCT06972719 is sponsored by Duke University. The principal investigator is Laura Havrilesky at Duke University. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology