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Recruiting NCT05534009

Health Care Workers Cohort Study in the EuCARE Project (EuCARE-HCW)

Trial Parameters

Condition COVID-19
Sponsor Euresist Network GEIE
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,800
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2022-04-01
Completion 2025-12-15
Interventions
Follow up of the first known immunization event

Brief Summary

The WP3 healthcare workers cohort in EuCARE is an observational multicentre study including collection of retrospective (historical) and prospective data and sample collection from health care workers with either a vaccination or a confirmed SARS-CoV-2 infection. Samples from HCW are sent to central laboratories for WP2 study were the impact of different variants in humoral and cellular immunity is to be analysed by biostatistical methods and with artificial intelligence in WP5. This analysis will focus on the impact on vaccine escape of viral variants / viral sequences as well as on any escape from any combination of natural and vaccine induced immunity. Eight countries will participate (Portugal, Italy, Germany, Lithuania, Georgia, Russia, Vietnam and Mexico).

Eligibility Criteria

Inclusion Criteria: The study subjects will be selected based on the following inclusion criteria: 1. Adult (\>18 years) HCW with mandatory information on their SARS-CoV-2 infection and vaccination status. 2. For those with a history of SARS-CoV-2 infection, diagnosis obtained by detection of SARS-CoV-2 RNA 3. Having a signed informed consent when required by ethical approval Exclusion Criteria: NONE

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