NCT07380906 geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry
| NCT ID | NCT07380906 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Joint & Vascular Institute |
| Condition | Knee Osteoarthristis |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,200 participants |
| Start Date | 2025-07-16 |
| Primary Completion | 2030-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,200 participants in total. It began in 2025-07-16 with a primary completion date of 2030-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The main questions it aims to answer are: 1. Does GAE lead to sustained improvement in pain (WOMAC, VAS) and quality-of-life scores over 12-36 months? 2. What patient or procedural factors are associated with better outcomes after GAE? Participants will: * Undergo GAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.
Eligibility Criteria
Inclusion Criteria: * Adults (≥18 years) with symptomatic KOA refractory to medical therapy, referred for GAE. Exclusion Criteria: * Pregnancy, coagulopathy, severe comorbidities, or inability to consent.
Frequently Asked Questions
Who can join the NCT07380906 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Knee Osteoarthristis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07380906 currently recruiting?
Yes, NCT07380906 is actively recruiting participants. Visit ClinicalTrials.gov or contact Joint & Vascular Institute to inquire about joining.
Where is the NCT07380906 trial being conducted?
This trial is being conducted at Libertyville, United States.
Who is sponsoring the NCT07380906 clinical trial?
NCT07380906 is sponsored by Joint & Vascular Institute. The trial plans to enroll 1,200 participants.