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Recruiting NCT06141135

NCT06141135 GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial

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Clinical Trial Summary
NCT ID NCT06141135
Status Recruiting
Phase
Sponsor Genomic Prediction Inc.
Condition Infertility, Female
Study Type INTERVENTIONAL
Enrollment 240 participants
Start Date 2023-11-15
Primary Completion 2025-11-15

Trial Parameters

Condition Infertility, Female
Sponsor Genomic Prediction Inc.
Study Type INTERVENTIONAL
Phase N/A
Enrollment 240
Sex FEMALE
Min Age 35 Years
Max Age 40 Years
Start Date 2023-11-15
Completion 2025-11-15
Interventions
Preimplantation genetic testing for aneuploidy (PGTA)

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Brief Summary

The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40 years of age.

Eligibility Criteria

Inclusion Criteria: * Women undergoing IVF of between 35 and 40 years of age at IVF cycle start * Utilization of Intracytoplasmic Sperm Injection ICSI (recommended) or ---Traditional IVF * Utilization of ejaculated or testicular sperm * Utilization of autologous or donor sperm * All Controlled Ovarian Hyperstimulation (COH) protocols Exclusion Criteria: * Utilization of donor oocytes * Utilization of gestational carrier * Recurrent Pregnancy Loss (RPL) defined as ≥ 3 consecutive miscarriages * Recurrent Implantation Failure (RIF) defined as ≥ 3 more failed embryo transfers * Preimplantation genetic testing for monogenic/single gene disorders (PGT-M) * Translocation carriers

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